Oomman Abraham, Ramachandran P, Subramanian Priya, Nagaraj B M S
Apollo Hospital, Gream's Road, Chennai 600 006.
J Indian Med Assoc. 2003 Apr;101(4):227-8.
Circadian variations in the incidence of hypertension and coronary events are well known with early morning surges. Effect of lunar cycles on various medical illnesses like seizures and psychiatric disturbances are documented. However, the effect of lunar cycles on coronary events has been sparsely documented. The authors studied the incidence of acute coronary events and admission patterns in the departments of emergency medicine and cardiology. Inclusion criteria included unstable angina, non-ST elevation myocardial infarction (MI) and ST elevation MI. Exclusion criteria included chest pain syndromes which were subsequently deemed non-cardiac by invasive or non-invasive investigations. Data from 1999 to 2001 were analysed. Admissions on full moon days were compared with those on new moon days. There were 30 full moon days and 30 new moon days and 223 admissions on full moon days and 266 on new moon days. This difference was statistically significant [p = .005]. Sixty-seven per cent were males and the rest were females. Subgroup analysis of mortality, postinfarction angina, effect on diabetics and hypertensives were done which showed an increased trend in new moon days. It is concluded that there is increased incidence of acute coronary events associated with new moon days.
高血压和冠状动脉事件的发生率存在昼夜节律变化，清晨血压会急剧上升，这是众所周知的。月球周期对癫痫发作和精神障碍等各种疾病的影响已有文献记载。然而，月球周期对冠状动脉事件的影响却鲜有文献记录。作者研究了急诊科和心内科急性冠状动脉事件的发生率及入院模式。纳入标准包括不稳定型心绞痛、非ST段抬高型心肌梗死（MI）和ST段抬高型MI。排除标准包括经侵入性或非侵入性检查后被认为非心脏性的胸痛综合征。分析了1999年至2001年的数据。将满月日的入院人数与新月日的入院人数进行了比较。共有30个满月日和30个新月日，满月日有223例入院，新月日有266例入院。这种差异具有统计学意义[p = .005]。67%为男性，其余为女性。对死亡率、梗死后心绞痛、对糖尿病患者和高血压患者的影响进行了亚组分析，结果显示新月日有上升趋势。得出的结论是，新月日与急性冠状动脉事件的发生率增加有关。
