组织对根管系统细菌的一种成分：脂磷壁酸的反应。
Tissue reactions to a component of root canal system bacteria: lipoteichoic acid.
作者信息
Costa Edson Dias Júnior, de Souza-Filho Francisco José, Barbosa Sérgio Valmor
机构信息
Division of Endodontics, Faculty of Dentistry, University of Brasília, Brasília, DF, Brazil.
出版信息
Braz Dent J. 2003;14(2):95-8. doi: 10.1590/s0103-64402003000200004.
Lipoteichoic acid (LTA), present in Gram-positive microorganisms, has physiochemical characteristics that allow it to act as an immunogen. Due to polymicrobial characteristics of root canal infections, LTA can participate in the development of periapical disease. The reaction of the rat subcutaneous tissue to Teflon tube implants, filled with Fibrinol soaked in lipoteichoic acid (concentration of 150 microg/ml), was observed. Lipoteichoic acid provoked an inflammatory tissue reaction.
存在于革兰氏阳性微生物中的脂磷壁酸（LTA）具有使其能够作为免疫原发挥作用的理化特性。由于根管感染具有多种微生物的特性，LTA可参与根尖周病的发展。观察了大鼠皮下组织对填充有浸泡在脂磷壁酸（浓度为150微克/毫升）中的纤维蛋白溶酶的特氟龙管植入物的反应。脂磷壁酸引发了炎症组织反应。
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