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用多普勒血流速度测量胎儿应激时的心输出量再分布。

Doppler flow velocity to measure the redistribution of fetal cardiac output in fetal stress.

作者信息

Scharf Alexander, Seppelt Martina, Sohn Christof

机构信息

Department I, Women's University Clinic, Medizinische Hochschule Hannover, Frauenklinik im Oststadtkrankenhaus, Podbielskistr. 380, D-30659 Hannover, Germany.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2003 Sep 22;110 Suppl 1:S119-26. doi: 10.1016/s0301-2115(03)00182-9.

Abstract

The pathophysiologic continuum of poor uterine and placental blood flow associated with fetal growth restriction has to be considered the major cause of poor birth outcomes. The main attention in this context is drawn to the possibilities of an early diagnosis of imminent fetal compromise prior to and under delivery. With regard to this, the detection of a reduced fetal oxygen saturation (fetal stress) plays a crucial role, whereas an acute incident causing fetal hypoxemia has to be differentiated from a chronic hypoxemic condition. An acute hypoxemia under delivery is best detected by cardiotocography. Due to its infrequent and unpredictable occurrence, an acute antenatal hypoxemia usually escapes common surveillance methods. Fetal biometry and pulsed Doppler sonography are to be considered the most suitable methods to diagnose chronic hypoxemic fetal conditions. The interrogation of a combination of peripheral and central vessels allow the sonologist to characterize the extend of a progressively deteriorating oxygen supply. However, this correlation is not yet completely understood. Therefore, clinical consequences still have to be drawn by cardiotocographic findings indicating a global cardiac decompensation.

摘要

与胎儿生长受限相关的子宫和胎盘血流不佳的病理生理连续过程,必须被视为导致不良出生结局的主要原因。在此背景下,主要关注点在于在分娩前及分娩过程中早期诊断即将发生的胎儿窘迫的可能性。就此而言,检测胎儿氧饱和度降低(胎儿应激)起着关键作用,而必须将导致胎儿低氧血症的急性事件与慢性低氧血症状态区分开来。分娩时的急性低氧血症最好通过胎心监护来检测。由于其发生频率低且不可预测,急性产前低氧血症通常会逃过常规监测方法。胎儿生物测量和脉冲多普勒超声检查被认为是诊断慢性低氧血症胎儿状况的最合适方法。对外周血管和中心血管的联合检查可使超声科医生描述逐渐恶化的氧气供应程度。然而,这种相关性尚未完全被理解。因此,仍需根据提示整体心脏失代偿的胎心监护结果得出临床结论。

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