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升主动脉和主动脉弓手术中的低温循环骤停:不同脑灌注技术及其他脑保护方法的理论影响

Hypothermic circulatory arrest during ascending and aortic arch surgery: the theoretical impact of different cerebral perfusion techniques and other methods of cerebral protection.

作者信息

Hagl Christian, Khaladj Nawid, Karck Matthias, Kallenbach Klaus, Leyh Rainer, Winterhalter Michael, Haverich Axel

机构信息

Division of Thoracic and Cardiovascular Surgery, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany.

出版信息

Eur J Cardiothorac Surg. 2003 Sep;24(3):371-8. doi: 10.1016/s1010-7940(03)00337-3.

Abstract

Operations on the thoracic aorta using hypothermic circulatory arrest are still associated with significant morbidity and mortality due to neurological complications. During the last decades, different cerebral protection techniques have been introduced into clinical practice to reduce the incidence of such complications. Furthermore clinical as well as basic researches have been performed to improve the outcome after these operations. Currently different cerebral perfusion methods are in clinical use and the superiority of one or the other method is a matter of controversial discussion. This review has been undertaken to evaluate the theoretical impact of these different methods of cerebral protection. Based on the experience of the authors the pros and cons are discussed with clinical and experimental reports from the literature.

摘要

由于神经并发症,使用低温循环停止技术进行胸主动脉手术仍与显著的发病率和死亡率相关。在过去几十年中,不同的脑保护技术已被引入临床实践以降低此类并发症的发生率。此外,还进行了临床和基础研究以改善这些手术后的结果。目前,不同的脑灌注方法正在临床中使用,而哪种方法更具优势是一个有争议的讨论话题。本综述旨在评估这些不同脑保护方法的理论影响。基于作者的经验,结合文献中的临床和实验报告对利弊进行了讨论。

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