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科威特缺血性中风的危险因素、亚型及预后——一项基于医院的研究

Risk factors, subtypes and outcome of ischaemic stroke in Kuwait--a hospital-based study.

作者信息

Al-Shammri S, Shahid Z, Ghali A, Mehndiratta M M, Swaminathan T R, Chadha G, Sharma P N, Akanji A O

机构信息

Department of Medicine, Faculty of Medicine, Kuwait University, Safat, Kuwait.

出版信息

Med Princ Pract. 2003 Oct-Dec;12(4):218-23. doi: 10.1159/000072287.

Abstract

OBJECTIVE

To report on stroke subtypes, associated risk factors and outcome in Kuwait.

METHODS

The records of 62 patients (30 male, 32 female) admitted with diagnosis of stroke to Kuwait Oil Company Hospital, Kuwait, a tertiary care hospital, during a 5-year period (1995-1999), were retrospectively reviewed.

RESULTS

Small artery infarction was the most common subtype and occurred in 37 subjects (59.7%); less common were atherosclerotic large artery strokes (19 patients, 30.6%) and strokes of cardio-embolic origin (6 patients, 9.7%). Identifiable risk factors or associated morbidities were hypertension (72.5%), diabetes mellitus (69.4%), ischaemic heart disease (14.5%), history of migraine (8.1%), lone atrial fibrillation (5.0%), and valvular heart disease (1.6%). The most important determinants of a deleterious 30-day outcome, as indicated by severe disability or death, were female gender, lack of use of anti-platelet drugs, presence of a large artery infarction stroke subtype, and cardio-embolic stroke.

CONCLUSION

Prevalence of hypertension and diabetes is high among patients with stroke in Kuwait, with rates higher than those found in any previous reports from the Gulf region. Two unusual observations were that women had a rather high frequency of stroke, and infarction of the small artery was more common than that of the large artery. Outcome, as indicated by severe disability or death, was worse among women, elderly patients, and those with large artery atherosclerotic and cardio-embolic strokes. There is some evidence that such a deleterious outcome might be ameliorated with use of anti-platelet drugs.

摘要

目的

报告科威特的卒中亚型、相关危险因素及预后情况。

方法

回顾性分析科威特石油公司医院(一家三级医疗机构)在1995年至1999年5年期间收治的62例确诊为卒中患者(30例男性,32例女性)的病历。

结果

小动脉梗死是最常见的亚型,有37例患者(59.7%);动脉粥样硬化性大动脉卒中(19例患者,30.6%)和心源性栓塞性卒中(6例患者,9.7%)相对少见。可识别的危险因素或相关疾病有高血压(72.5%)、糖尿病(69.4%)、缺血性心脏病(14.5%)、偏头痛病史(8.1%)、孤立性房颤(5.0%)和瓣膜性心脏病(1.6%)。严重残疾或死亡所表明的30天不良预后的最重要决定因素是女性、未使用抗血小板药物、存在大动脉梗死性卒中亚型和心源性栓塞性卒中。

结论

科威特卒中患者中高血压和糖尿病的患病率较高,高于海湾地区以往任何报告中的患病率。两个不寻常的发现是女性卒中发生率相当高,且小动脉梗死比大动脉梗死更常见。严重残疾或死亡所表明的预后在女性、老年患者以及患有大动脉粥样硬化性和心源性栓塞性卒中的患者中更差。有证据表明,使用抗血小板药物可能改善这种不良预后。

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