MMWR Morb Mortal Wkly Rep. 2003 Sep 5;52(35):837-40.
During late January 2003, the Michigan Department of Community Health (MDCH) received reports of severe unexplained illnesses and deaths in children and young adults aged <21 years residing in Michigan. Subsequently, two of the deaths were found to be associated with influenza, including one with neurologic complications. To identify cases of severe influenza in otherwise healthy children and young adults aged <21 years, MDCH conducted enhanced surveillance for influenza-associated illness. This report summarizes the findings of this ongoing investigation, which indicate the need to better define the frequency of serious complications from influenza in healthy children and to incorporate such findings into evaluations of current vaccine recommendations for children.
2003年1月下旬，密歇根州社区卫生部（MDCH）收到报告，称居住在密歇根州的21岁以下儿童和年轻人中出现了不明原因的严重疾病和死亡情况。随后，发现其中两例死亡与流感有关，包括一例伴有神经系统并发症。为了确定21岁以下健康儿童和年轻人中的重症流感病例，MDCH对流感相关疾病开展了强化监测。本报告总结了这项正在进行的调查结果，结果表明有必要更好地界定健康儿童流感严重并发症的发生率，并将这些结果纳入对当前儿童疫苗接种建议的评估中。
