Fel'dman S Z, Kagan Iu D, Usviatsov B Ia, Parshuta L I
Institute of Cellular and Intracellular Symbiosis, Medical Academy, Municipal Clinical Infectious Hospital, Orenburg, Russia.
Zh Mikrobiol Epidemiol Immunobiol. 2003 Jul-Aug(4):59-60.
The persistence properties of 70 S. enteriditis cultures and 12 S. typhimurium cultures isolated from the feces of children of the earliest age groups with the gastrointestinal form of Salmonellosis infection were studied. The study revealed that the low level of persistence properties occurred in most cases of mild forms of the disease. Salmonellae with a high level of anticomplement and antilysozyme activity were more often isolated in cases of moderate and severe forms of salmonellosis. The presence of correlation between the expression of the factors under study and the severity of the symptoms of intoxication in combination with the duration of the diarrhea syndrome in moderate and severe forms of Salmonella infection in children of the earliest age groups was established. The suggestion was made that the evaluation of the persistence properties of bacteria may be used for the prognosis of the course of the infectious process.
对从感染沙门氏菌病胃肠型的最年幼儿童粪便中分离出的70株肠炎沙门氏菌培养物和12株鼠伤寒沙门氏菌培养物的持续存在特性进行了研究。研究发现，在大多数轻症病例中，细菌的持续存在特性水平较低。在中度和重度沙门氏菌病病例中，更常分离出具有高抗补体和抗溶菌酶活性的沙门氏菌。确定了在最年幼儿童中度和重度沙门氏菌感染中，所研究因素的表达与中毒症状严重程度以及腹泻综合征持续时间之间存在相关性。有人提出，评估细菌的持续存在特性可用于预测感染过程的病程。
