Katircioglu Yasemin A, Budak Koray, Salvarli Sibel, Duman Sunay
Ankara Education and Research Hospital, Ankara, Turkey.
Jpn J Ophthalmol. 2003 Sep-Oct;47(5):519-22. doi: 10.1016/s0021-5155(03)00109-6.
To evaluate the efficiency of preserved human amniotic membrane transplantation for conjunctival surface reconstruction in cases of chemical burn.
Preserved amniotic membrane transplantation was performed in 6 patients (6 eyes) having symblepharon and fornix insufficiency due to chemical burn. Amniotic membrane was sutured to the intact conjunctiva after the fibrotic tissue was excised. The fornix was reconstructed in cases having fornix insufficiency. These cases were followed up for 4-24 months.
During the mean follow-up period (10+/-7.37 months) adequate bulbar conjunctiva and fornix depth was achieved in 5 patients without recurrence and with mild fibrosis. In 1 patient who did not have a healthy conjunctiva preoperatively, conjunctival fibrosis and symblepharon recurred.
Preserved human amniotic membrane transplantation is a good alternative treatment method for conjunctival surface reconstruction in those cases with some healthy peripheral conjunctival tissue.
评估保存的人羊膜移植在化学烧伤病例中结膜表面重建的有效性。
对6例因化学烧伤导致睑球粘连和穹窿部不足的患者(6只眼)进行保存的羊膜移植。切除纤维化组织后,将羊膜缝合至完整的结膜。对穹窿部不足的病例进行穹窿部重建。对这些病例进行了4至24个月的随访。
在平均随访期(10±7.37个月)内,5例患者获得了足够的球结膜和穹窿深度,无复发且纤维化轻微。1例术前无健康结膜的患者出现结膜纤维化和睑球粘连复发。
对于有一些健康周边结膜组织的病例,保存的人羊膜移植是结膜表面重建的一种良好替代治疗方法。