Basaria Shehzad, Krop Julie S, Braga-Basaria Milena
Division of Endocrinology and Metabolism, Johns Hopkins University School of Medicine, Bayview Medical Center, 4940 Eastern Avenue, B-Building, Suite 114, Baltimore, MD 21224, USA.
Mt Sinai J Med. 2003 Sep;70(4):265-7.
Pituitary stalk involvement is seen in a variety of medical conditions such as infectious diseases, infiltrative diseases and tumors (intracranial and metastatic). Metastatic cancer has a greater propensity to involve the infundibulum and neurohypophysis. We report a case of a 68-year-old man who presented with thickening of the stalk, panhypopituitarism, diabetes insipidus and generalized lymphadenopathy. Lymphoma was diagnosed on axillary lymph node biopsy and lymphomatous involvement of the infundibulum was suspected. Although infundibular thickening resolved and diabetes insipidus improved after chemotherapy, panhypopituitarism persisted.
垂体柄受累可见于多种医学病症，如传染病、浸润性疾病和肿瘤（颅内肿瘤和转移性肿瘤）。转移性癌症更易累及漏斗部和神经垂体。我们报告一例68岁男性病例，该患者出现垂体柄增粗、全垂体功能减退、尿崩症和全身淋巴结肿大。经腋窝淋巴结活检诊断为淋巴瘤，怀疑漏斗部有淋巴瘤累及。尽管化疗后漏斗部增粗消退且尿崩症有所改善，但全垂体功能减退仍持续存在。
