Engst R, Linzbach P
MMW Munch Med Wochenschr. 1976 Jan 9;118(2):43-6.
A report is made on 80 male patients aged 19-25 and suffering from common acne, who were treated with vitamin A acid (Eudyna) partly as inpatients and partly as outpatients. All stages were present from acne comedonica to acne conglobata. The preparation was available in the form of cream and jelly, each containing 0.05% tretinoin. As a rule, the drug was applied once daily. At the end of the tretinoin treatment lasting for a maximum of 9 weeks, a decrease in comedones of more than 90% is reported. The tolerance of Eudyna was seen to be good to very good in more than two thirds of the patients.
报告了80名年龄在19至25岁之间患有寻常痤疮的男性患者,他们部分作为住院患者、部分作为门诊患者接受了维甲酸(优脱欣)治疗。痤疮从粉刺到聚合性痤疮的各个阶段均有出现。该制剂有乳膏和凝胶两种剂型,每种均含有0.05%的维甲酸。通常,药物每日使用一次。在最长持续9周的维甲酸治疗结束时,报告称粉刺减少了90%以上。超过三分之二的患者对优脱欣的耐受性良好至极佳。