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实验动物急性弓形虫病的病理学研究

Pathologic study of acute toxoplasmosis in experimental animals.

作者信息

Sukthana Yaowalark, Waree Phuangphet, Pongponratn Emsri, Chaisri Urai, Riganti Mario

机构信息

Department of Protozoology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

出版信息

Southeast Asian J Trop Med Public Health. 2003 Mar;34(1):16-21.

Abstract

We studied the pathology of acute toxoplasmosis in experimental mice inoculated with RH strain tachyzoites of Toxoplasma gondii. All died from severe disseminated toxoplasmosis involving the liver, spleen and pancreas. Pathological features of acute toxoplasmosis in susceptible mice could be regarded as an excellent model for acute reactivation of Toxoplasma in the immunosuppressed host.

摘要

我们研究了接种刚地弓形虫RH株速殖子的实验小鼠急性弓形虫病的病理学。所有小鼠均死于严重的播散性弓形虫病,累及肝脏、脾脏和胰腺。易感小鼠急性弓形虫病的病理特征可被视为免疫抑制宿主中弓形虫急性再激活的极佳模型。

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