硫酸脱氢表雄酮的代谢清除率。VI. 子痫研究。
Metabolic clearance rate of dehydroisoandrosterone sulfate. VI. Studies of eclampsia.
作者信息
Gant N F, Madden J D, Chand S, Worley R J, Siiteri P K, MacDonald P C
出版信息
Obstet Gynecol. 1976 Mar;47(3):327-30.
The metabolic clearance rate of dehydroisoandrosterone sulfate (MCRDS) was measured in 11 women during an eclamptic episode, and the subjects were then followed for at least 5 years. The MCRDS was usually decreased in primigravid women with eclampsia. However, in eclamptic primigravid women who later developed essential hypertension and/or recurrent hypertension in subsequent pregnancies the MCRDS was elevated. Also, in multiparous women with chronic essential hypertension plus superimposed eclampsia, the MCRDS was increased to above normal values.
在11名子痫发作期的女性中测量了硫酸脱氢表雄酮的代谢清除率（MCRDS），然后对这些受试者进行了至少5年的随访。子痫初产妇的MCRDS通常会降低。然而，在子痫初产妇中，那些后来在随后的妊娠中发展为原发性高血压和/或复发性高血压的患者，其MCRDS会升高。此外，在患有慢性原发性高血压并伴有子痫的经产妇中，MCRDS会升高至高于正常值。
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