van den Bergh Alfons C M, Hoving Marjanke A, Links Thera P, Dullaart Robin P F, Ranchor Adelita V, ter Weeme Cees A, Canrinus Alof A, Szabó Ben G, Pott Jan Willem R
Department of Radiation Oncology, University Hospital Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.
Radiother Oncol. 2003 Aug;68(2):101-3. doi: 10.1016/s0167-8140(03)00201-9.
For diagnosing radiation optic neuropathy (RON) ophthalmological and imaging data were evaluated from 63 acromegalic patients, irradiated between 1967 and 1998. Two patients developed RON: one patient in one optic nerve 10 years and another patient in both optic nerves 5 months after radiation therapy. RON is a rare complication after external beam radiation therapy for acromegaly, which can occur after a considerable latency period.
为诊断放射性视神经病变（RON），我们评估了1967年至1998年间接受过放疗的63例肢端肥大症患者的眼科和影像学数据。两名患者发生了RON：一名患者在放疗后10年单眼视神经发病，另一名患者在放疗后5个月双眼视神经发病。RON是肢端肥大症外照射放疗后一种罕见的并发症，可在相当长的潜伏期后发生。
