Bíres J, Bartko P, Juhásová Z, Kovárová E
Univerzita veterinárskeho lekárstva, Kosice.
Vet Med (Praha). 1992 Dec;37(12):641-50.
The effects of an administration of the Zindep inj. preparation (Biotika) were evaluated in pregnant dairy cows as exerted on specific weight, total protein (TP) content, total immunoglobulin (IgC) and albumin (ALB) contents in colostrum. These parameters were also followed: calf's health, live weight, leucocyte (Lc) counts, T-lymphocyte (T-Ly) counts, contents of TPs, IgCs and ALBs in the blood serum of calves. Zinc concentrations were determined in colostrum, milk and calf blood serum. Our observations included 16 dairy cows in the seventh month of pregnancy in the second lactation and their calves in the winter feeding season. Eight experimental dairy cows were treated with the Zindep preparation in form of an injection to the neck muscles at a dose of 3 mg Zn/kg live weight in the mid-seventh month of pregnancy. Blood samples were taken from v. jugularis from all calves before their first drinking, on days 5, 15 and 30 of age. Colostrum, and/or milk samples were obtained by drawing of the colostrum or milk from the udder quarters within 60 minutes after parturition, on days 5 and 15 of lactation. Zn levels at birth were 16.48 +/- 2.67 mumol/l in experimental calves and 13.84 +/- 3.19 mumol/l in control calves. Zincaemia decreased slightly in both groups on days 5 and 15 of age, but it was insignificantly higher in calves coming from Zindep-treated dairy cows. Zn levels in the blood serum on the 30th day of age were 18.45 +/- 2.44 mumol/l in experimental animals and 15.73 +/- 3.11 mumol/l in control animals. Zn content in the colostrum of experimental cows was 2.40 +/- 0.42 mg/l and in the control it was 1088 +/- 0.52 mg/l (P < 0.05). On day 5 of lactation, Zn amounts in the milk of experimental dairy cows decreased to 0.95 +/- 0.12 mg/l and to 0.76 +/- 0.10 mg/l in the control (P < 0.01). Zn levels in the milk of experimental cows on day 15 of lactation were 0.95 +/- 0.13 mg/l and in the milk of control group they were 0.82 +/- 0.14 mg/l. Colostrum specific weight from zinc-treated cows was 1,067.86 +/- 0.75 g/cm3 and 1,056.8 +/- 13.53 g/cm3 in the control. TP and IgC concentrations were 137.81 +/- 38.11 g/l and 110.13 +/- 29.91 U ZST, respectively, in the colostrum of experimental group, and 105.98 +/- 32.02 g/l and 85.53 +/- 25.42 U ZST, resp., in control animals.(ABSTRACT TRUNCATED AT 400 WORDS)
对怀孕奶牛注射Zindep注射液(Biotika),评估其对初乳中比重、总蛋白(TP)含量、总免疫球蛋白(IgC)和白蛋白(ALB)含量的影响。还对以下参数进行了跟踪:犊牛的健康状况、体重、白细胞(Lc)计数、T淋巴细胞(T-Ly)计数,以及犊牛血清中TP、IgC和ALB的含量。测定了初乳、牛奶和犊牛血清中的锌浓度。观察对象包括16头处于第二泌乳期、怀孕七个月的奶牛及其犊牛,处于冬季饲养期。八头实验奶牛在怀孕第七个半月时,以3毫克锌/千克体重的剂量颈部肌肉注射Zindep制剂。在所有犊牛首次饮用初乳前、5日龄、15日龄和30日龄时,从颈静脉采集血样。在分娩后60分钟内从乳腺各象限采集初乳和/或牛奶样本,分别在泌乳第5天和第15天采集。实验犊牛出生时的锌水平为16.48±2.67微摩尔/升,对照犊牛为13.84±3.19微摩尔/升。两组犊牛在5日龄和15日龄时锌血症均略有下降,但来自接受Zindep治疗奶牛的犊牛锌血症略高,差异不显著。实验动物30日龄时血清锌水平为18.45±2.44微摩尔/升,对照动物为15.73±3.11微摩尔/升。实验奶牛初乳中的锌含量为2.40±0.42毫克/升,对照奶牛为1088±0.52毫克/升(P<0.05)。泌乳第5天,实验奶牛牛奶中的锌含量降至0.95±0.12毫克/升,对照奶牛降至0.76±0.10毫克/升(P<0.01)。实验奶牛泌乳第15天牛奶中的锌水平为0.95±0.13毫克/升,对照组牛奶中为0.82±0.14毫克/升。经锌处理奶牛的初乳比重为1067.86±0.75克/立方厘米,对照奶牛为1056.8±13.53克/立方厘米。实验组初乳中TP和IgC浓度分别为137.81±38.11克/升和110.13±29.91 U ZST,对照动物分别为105.98±32.02克/升和85.53±25.42 U ZST。(摘要截于400字)