维持性电休克治疗对认知功能的影响。
Effects of maintenance electroconvulsive therapy on cognitive functions.
作者信息
Vothknecht S, Kho K H, van Schaick H W, Zwinderman A H, Middelkoop H, Blansjaar B A
机构信息
GGZ Delfland, Delft, The Netherlands.
出版信息
J ECT. 2003 Sep;19(3):151-7. doi: 10.1097/00124509-200309000-00007.
BACKGROUND
This study examined cognitive side effects of maintenance electroconvulsive (ECT) in comparison with maintenance pharmacotherapy after index ECT.
METHOD
Clinical outcome data and neuropsychological measurements were compared in 11 maintenance ECT patients and 13 control patients treated with maintenance pharmacotherapy after index ECT. Data were gathered in a prospective naturalistic study during follow-up.
RESULTS
There were no significant differences in patient characteristics and effects of index ECT between groups. In control patients treated with maintenance pharmacotherapy, cognitive function as well as depression ratings remained stable. During maintenance ECT neuropsychological test performance and depression ratings improved slightly but not significantly.
CONCLUSIONS
Neuropsychological functioning during the maintenance phase of treatment did not differ between the two treatment groups. Cognitive function remained stable during maintenance ECT.
背景
本研究比较了维持性电休克治疗（ECT）与首次ECT后维持性药物治疗的认知副作用。
方法
对11例接受维持性ECT的患者和13例首次ECT后接受维持性药物治疗的对照患者的临床结局数据和神经心理学测量结果进行了比较。数据是在随访期间的一项前瞻性自然研究中收集的。
结果
两组患者的特征及首次ECT的效果无显著差异。接受维持性药物治疗的对照患者的认知功能以及抑郁评分保持稳定。在维持性ECT期间，神经心理学测试表现和抑郁评分略有改善，但不显著。
结论
两个治疗组在治疗维持阶段的神经心理学功能无差异。维持性ECT期间认知功能保持稳定。
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