Abdelhamid A M, Dorra T M
Department of Animal and Poultry Production, Mansoura University, Egypt.
Arch Tierernahr. 1992;42(2):133-45. doi: 10.1080/17450399209432983.
Feeding broiler chicks on graded levels of fluorine (0, 25, 125, 625 and 3125 ppm F) from NaF for 4 weeks (4-7 weeks of age) resulted in various alterations which depended on the level of contamination. The main changes included poor growth and feed conversion, high mortality rate, disorders of bone formation, decreased relative weights of pituitary, adrenal, heart, liver, spleen, lungs, kidneys and gizzard and changes in intestinal dimensions. Also, the biochemical tests revealed other kinds of physiological disfunction mainly in the form of anaemia (low haematocrit, haemoglobin, total protein, albumin and globulin fractions), intoxication (increased methaemoglobin), nephrotic (raised phosphorus and magnesium) and hepatic (elevated lipoproteins and lowering enzymatic activity) disfunctions. The general observations and postmortem examination confirmed also the biochemical findings which revealed the harmful effect of feedborne-fluorine intoxication in broiler chicks.
用不同氟含量(0、25、125、625和3125 ppm氟,以氟化钠形式提供)的饲料喂养4周龄(4 - 7周龄)的肉鸡雏鸡,会导致各种变化,这些变化取决于污染水平。主要变化包括生长不良和饲料转化率低、死亡率高、骨形成紊乱、垂体、肾上腺、心脏、肝脏、脾脏、肺、肾脏和砂囊的相对重量下降以及肠道尺寸改变。此外,生化测试还揭示了其他类型的生理功能障碍,主要表现为贫血(血细胞比容、血红蛋白、总蛋白、白蛋白和球蛋白组分降低)、中毒(高铁血红蛋白增加)、肾病(磷和镁升高)和肝病(脂蛋白升高和酶活性降低)功能障碍。总体观察和尸检也证实了生化检查结果,这些结果揭示了饲料源性氟中毒对肉鸡雏鸡的有害影响。