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重组活化凝血因子 VII 用于体外肺支持依赖型呼吸衰竭双侧肺移植术后大出血。

Recombinant activated factor VII for exsanguinating haemorrhage post bilateral lung transplantation for extra-corporeal lung support-dependent respiratory failure.

作者信息

Lucey M A, Myburgh J A

机构信息

Intensive Care Unit, St George Hospital, Sydney, New South Wales.

出版信息

Anaesth Intensive Care. 2003 Aug;31(4):465-9.

PMID:12973973
Abstract

Following three weeks of extracorporeal lung support for acute respiratory distress syndrome, a 15-year-old male underwent bilateral lung transplantation. This procedure was complicated by massive postoperative haemorrhage. The administration of recombinant activated Factor VII was associated with improved haemostasis. However, development of cardiac tamponade soon after injection required emergency exploration and evacuation of a large mediastinal clot.

摘要

在对一名急性呼吸窘迫综合征患者进行了三周的体外肺支持治疗后,一名15岁男性接受了双侧肺移植手术。该手术因术后大量出血而变得复杂。给予重组活化凝血因子VII后止血情况有所改善。然而,注射后不久出现了心脏压塞,需要紧急探查并清除大量纵隔血块。

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Recombinant activated factor VII for exsanguinating haemorrhage post bilateral lung transplantation for extra-corporeal lung support-dependent respiratory failure.重组活化凝血因子 VII 用于体外肺支持依赖型呼吸衰竭双侧肺移植术后大出血。
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Utilization of recombinant activated factor VII for intracranial hematoma evacuation in coagulopathic nonhemophilic neurosurgical patients with normal international normalized ratios.重组活化凝血因子 VII 在国际标准化比值正常的凝血功能障碍非血友病神经外科患者颅内血肿清除术中的应用。
Neurocrit Care. 2007;7(2):136-9. doi: 10.1007/s12028-007-0040-x.