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梗阻性胃十二指肠结核的外科治疗

Surgical management of obstructive gastroduodenal tuberculosis.

作者信息

Negi Sanjay Singh, Sachdev Ajay Kumar, Chaudhary Adarsh, Kumar Nirmal, Gondal Ranjana

机构信息

Department of Gastrointestinal Surgery, G.B. Pant Hospital, University of Delhi, New Delhi 110002, India.

出版信息

Trop Gastroenterol. 2003 Jan-Mar;24(1):39-41.

Abstract

BACKGROUND

Gastroduodenal tuberculosis is a rare but potentially curable condition. The aim of the present study was to evaluate the clinical presentation, pre-operative status, management and outcome in patients with histologically proven diagnosis of gastroduodenal obstruction due to tuberculosis.

METHODS

We retrospectively reviewed the records of 17 patients managed surgically for gastroduodenal obstruction due to tuberculosis.

RESULTS

The site of obstruction was the pyloroduodenal canal in 53% of patients, second part of the duodenum in 24%, third part of the duodenum in 12% and duodenjojejunal flexure in 12%. The obstruction was caused by fibrotic stricture formation in 59% of patients and extrinsic compression by a lymph nodal mass in 41%. Endoscopic biopsy was diagnostic in only 29% of the patients in whom it was performed. Overall, a pre-operative diagnosis of gastroduodenal tuberculosis was suspected in only 35% of patients. All the patients underwent surgical drainage procedures and the diagnosis was confirmed by histopathological examination of biopsies taken at the time of laparotomy.

CONCLUSIONS

In view of its rarity and non-specific findings on clinical, radiological and endoscopic evaluation, tuberculosis as a cause of gastroduodenal obstruction is seldom diagnosed pre-operatively. Hence, a high index of suspicion is required in young patients residing in endemic areas. Surgical intervention helps not only in relieving obstruction but also in confirming the diagnosis.

摘要

背景

胃十二指肠结核是一种罕见但可治愈的疾病。本研究的目的是评估经组织学证实因结核导致胃十二指肠梗阻患者的临床表现、术前状况、治疗及预后。

方法

我们回顾性分析了17例因结核导致胃十二指肠梗阻而接受手术治疗患者的病历。

结果

53%的患者梗阻部位在幽门十二指肠管,24%在十二指肠第二部,12%在十二指肠第三部,12%在十二指肠空肠曲。59%的患者梗阻由纤维化狭窄形成所致,41%由淋巴结肿块的外在压迫引起。仅29%接受内镜活检的患者通过活检确诊。总体而言,仅35%的患者术前怀疑胃十二指肠结核。所有患者均接受了手术引流,剖腹手术时所取活检的组织病理学检查证实了诊断。

结论

鉴于胃十二指肠结核的罕见性以及临床、影像学和内镜评估中缺乏特异性表现,术前很少能诊断出其为胃十二指肠梗阻的病因。因此,对于居住在流行地区的年轻患者,需要高度怀疑。手术干预不仅有助于解除梗阻,还能确诊疾病。

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