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印度西北部城乡血压正常及高血压人群中的孤立性脂质异常

Isolated lipid abnormalities in rural and urban normotensive and hypertensive north-west Indians.

作者信息

Malhotra P, Kumari Savita, Singh S, Varma S

机构信息

Dept. of Internal Medicine, Post Graduate Institute of Medical Education & Research, Chandigarh-160 012.

出版信息

J Assoc Physicians India. 2003 May;51:459-63.

Abstract

BACKGROUND

Lipid abnormalities are common in patients with hypertension. The prevalence of isolated lipid abnormalities is not known in normotensive and hypertensive population of north-west India.

METHODS

We studied the prevalence of isolated low high density lipoprotein cholesterol (IL-HDLC), isolated high low density lipoprotein cholesterol (IH-LDLC) and isolated high triglycerides (IH-TG) abnormalities among rural and urban normotensive and hypertensives of north-west India.

RESULTS

The prevalence of lipid abnormalities was 47.6% and 51.4% in rural normotensives and hypertensives and 43.8% and 46.8% in urban normotensives and hypertensives respectively. The prevalence of IL-HDLC varied from 3.8% to 23.7% among hypertensives and 19.4% to 30.4% among normotensives. The prevalence of IH-TG abnormalities was 11.8% to 18.8% among hypertensives and 7.0% to 15.4% among hypertensives. The prevalence of isolated high LDLC abnormalities was low (0.8-9.2%). There was no significant difference in these abnormalities in relation to age and sex except IH-LDLC in male hypertensives.

CONCLUSION

Isolated low HDLC and isolated high TG were the commonest isolated lipid abnormalities among rural and urban population of north-west India whereas isolated high LDLC was uncommon.

摘要

背景

脂质异常在高血压患者中很常见。在印度西北部的正常血压和高血压人群中,单纯脂质异常的患病率尚不清楚。

方法

我们研究了印度西北部农村和城市正常血压者及高血压患者中单纯低高密度脂蛋白胆固醇(IL-HDLC)、单纯高低密度脂蛋白胆固醇(IH-LDLC)和单纯高甘油三酯(IH-TG)异常的患病率。

结果

农村正常血压者和高血压患者的脂质异常患病率分别为47.6%和51.4%,城市正常血压者和高血压患者分别为43.8%和46.8%。高血压患者中IL-HDLC的患病率在3.8%至23.7%之间,正常血压者中为19.4%至30.4%。高血压患者中IH-TG异常的患病率在11.8%至18.8%之间,正常血压者中为7.0%至15.4%。单纯高LDLC异常的患病率较低(0.8-9.2%)。除男性高血压患者中的IH-LDLC外,这些异常在年龄和性别方面无显著差异。

结论

在印度西北部农村和城市人群中,单纯低HDLC和单纯高TG是最常见的单纯脂质异常,而单纯高LDLC则不常见。

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