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睫状体冷冻疗法作为原发性青光眼的一种替代治疗方法。

Cyclocryotherapy as an alternative treatment for primary glaucoma.

作者信息

Hennekes R, Belgrado G

机构信息

Dept. of Ophthalmology, A.Z.-V.U.B., Brussels, Belgium.

出版信息

Bull Soc Belge Ophtalmol. 1992;244:169-76.

PMID:1297510
Abstract

Cyclocryotherapy was used as an alternative treatment for primary glaucoma in a series of 56 patients, both with narrow and open angle. In this prospective study treatment was successful in 87.7% of the cases (Peak I.O.P. < or = 20 mm Hg) with a mean follow up period of 10.1 months. Mean intraocular tension decreased from 29.7 mm Hg preoperatively down to 17.25 mm Hg postoperatively. About 60% of the eyes, however, needed an additional local treatment. Postoperative complications were rare and mild. A conjunctival congestion, and a mild self limiting iridocyclitis, were the most frequent ones. Long term efficacy was evaluated retrospectively (21 eyes with primary glaucoma; mean follow up period: 51 months). 58.3% were still controlled today, the majority of them requiring local medication. A further deterioration of visual field, however, had been noticed in 26.6% of these "obviously normotensive eyes". Because of its good efficacy and its lack of severe complications as opposed to trabeculectomy cyclocryotherapy is suggested as a first choice treatment in primary glaucoma.

摘要

在一系列56例原发性青光眼患者(包括窄角和开角型)中,睫状体冷冻疗法被用作替代治疗方法。在这项前瞻性研究中,87.7%的病例治疗成功(眼压峰值≤20mmHg),平均随访期为10.1个月。平均眼压从术前的29.7mmHg降至术后的17.25mmHg。然而,约60%的眼睛需要额外的局部治疗。术后并发症罕见且轻微。结膜充血和轻度自限性虹膜睫状体炎是最常见的并发症。对长期疗效进行了回顾性评估(21例原发性青光眼患者;平均随访期:51个月)。如今仍有58.3%的患者病情得到控制,其中大多数需要局部用药。然而,在这些“明显眼压正常的眼睛”中,有26.6%的患者视野出现了进一步恶化。由于睫状体冷冻疗法与小梁切除术相比疗效良好且无严重并发症,因此建议将其作为原发性青光眼的首选治疗方法。

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