Abe E, Jin C H, Hong M H, Sato T, Shinki T, Suda T
Department of Biochemistry, School of Dentistry, Showa University, Tokyo, Japan.
J Nutr Sci Vitaminol (Tokyo). 1992;Spec No:88-91. doi: 10.3177/jnsv.38.special_88.
The third component of complement (C3) is a protein produced by osteoblastic cells in response to 1 alpha,25(OH)2D3. The bone C3 appears to be involved in differentiation of bone marrow cells into osteoclasts in concert with other vitamin D-dependent factors. Further studies are needed to understand the precise role of C3 in bone.
