Petrova N V, Bubnova M G, Aronov D M, Melkina O E, Olferév A M
Kardiologiia. 1992;32(11-12):59-62.
The impact of graded exercises of various intensity and duration on serum lipoprotein values was examined in 20 patients with coronary heart disease (CHD) and 10 healthy individuals after a single dietary fat load (FL). FL resulted in hypertriglyceridemia which was accompanied by elevated apo-AI levels and reduced apo-B/apo-AI ratio in the healthy persons, whereas it was accompanied by lower apo-AI levels and increased apo-B/apo-AI ratio in the patients. The short-term maximum exercise in the presence of FL caused negative shifts in the lipid transport system both in the healthy persons and the patients, by elevating the level of apo-B-containing lipoproteins. Yet, the healthy individuals showed a further increase in apo-AI concentrations. The long-term exercise in the training mode corrected changes in lipid values, which had been induced by FL in the two groups of the examinees. There was a decrease in the levels of triglycerides, low density lipoprotein, cholesterol and an increase in the level of high density lipoprotein cholesterol.
在20例冠心病(CHD)患者和10名健康个体中,研究了单次饮食脂肪负荷(FL)后不同强度和持续时间的分级运动对血清脂蛋白值的影响。FL导致健康人出现高甘油三酯血症,同时伴有载脂蛋白AI(apo-AI)水平升高和载脂蛋白B/载脂蛋白AI(apo-B/apo-AI)比值降低,而在患者中则伴有apo-AI水平降低和apo-B/apo-AI比值升高。在存在FL的情况下进行短期最大运动,通过提高含apo-B脂蛋白水平,使健康人和患者的脂质转运系统均出现负向变化。然而,健康个体的apo-AI浓度进一步升高。训练模式下的长期运动纠正了FL在两组受检者中引起的脂质值变化。甘油三酯、低密度脂蛋白、胆固醇水平降低,高密度脂蛋白胆固醇水平升高。