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[运动对缺血性心脏病患者饮食性高脂蛋白血症的影响]

[Impact of exercise on alimentary hyperlipoproteinemia in patients with ischemic heart disease].

作者信息

Petrova N V, Bubnova M G, Aronov D M, Melkina O E, Olferév A M

出版信息

Kardiologiia. 1992;32(11-12):59-62.

PMID:1297884
Abstract

The impact of graded exercises of various intensity and duration on serum lipoprotein values was examined in 20 patients with coronary heart disease (CHD) and 10 healthy individuals after a single dietary fat load (FL). FL resulted in hypertriglyceridemia which was accompanied by elevated apo-AI levels and reduced apo-B/apo-AI ratio in the healthy persons, whereas it was accompanied by lower apo-AI levels and increased apo-B/apo-AI ratio in the patients. The short-term maximum exercise in the presence of FL caused negative shifts in the lipid transport system both in the healthy persons and the patients, by elevating the level of apo-B-containing lipoproteins. Yet, the healthy individuals showed a further increase in apo-AI concentrations. The long-term exercise in the training mode corrected changes in lipid values, which had been induced by FL in the two groups of the examinees. There was a decrease in the levels of triglycerides, low density lipoprotein, cholesterol and an increase in the level of high density lipoprotein cholesterol.

摘要

在20例冠心病(CHD)患者和10名健康个体中,研究了单次饮食脂肪负荷(FL)后不同强度和持续时间的分级运动对血清脂蛋白值的影响。FL导致健康人出现高甘油三酯血症,同时伴有载脂蛋白AI(apo-AI)水平升高和载脂蛋白B/载脂蛋白AI(apo-B/apo-AI)比值降低,而在患者中则伴有apo-AI水平降低和apo-B/apo-AI比值升高。在存在FL的情况下进行短期最大运动,通过提高含apo-B脂蛋白水平,使健康人和患者的脂质转运系统均出现负向变化。然而,健康个体的apo-AI浓度进一步升高。训练模式下的长期运动纠正了FL在两组受检者中引起的脂质值变化。甘油三酯、低密度脂蛋白、胆固醇水平降低,高密度脂蛋白胆固醇水平升高。

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