Romagnoli C, Frezza S, De Carolis M P, Zecca E, Papacci P, Tortorolo G
Cattedra di Neonatologia, Università Cattolica del Sacro Cuore, Roma.
Minerva Pediatr. 1992 Nov;44(11):551-4.
The effectiveness of a new device for phototherapy in the treatment of nonhemolytic hyperbilirubinemia (Wallaby Phototherapy System) was evaluated. 46 healthy term infants, appropriate for gestational age and with serum bilirubin > 12 mg/dl in the first 3 days of life or > 15 mg/dl after 3rd day were randomly assigned to a treatment group (24 hours of light exposure with Wallaby Phototherapy System) and to a control group (any treatment for hyperbilirubinemia). Body temperature, weight, feeding and hydration were recorded during the study period. Serum bilirubin and haematocrit were done every 12 hours in all babies. In the treated group we found a decrease of 5.1% and of 7.8% at 12 and 24 hours, while an increase of 3.37% and of 2.9% at 12 and 24 hours was found in the control group. After 24 hours the serum bilirubin level was significantly lower in the treated group than in the control group (p < 0.05). No newborn of the treated group needed conventional phototherapy versus 4 control infants (17.4%). The conclusion of our study is that the Wallaby System is useful in the treatment of neonatal nonhemolytic hyperbilirubinemia even if its effectiveness for higher bilirubin levels has still to be tested.
对一种用于光疗的新设备（小袋鼠光疗系统）治疗非溶血性高胆红素血症的有效性进行了评估。46名健康足月儿，胎龄合适，出生后第1天血清胆红素>12mg/dl或第3天后>15mg/dl，被随机分为治疗组（使用小袋鼠光疗系统进行24小时光照）和对照组（任何高胆红素血症治疗）。在研究期间记录体温、体重、喂养和水合情况。所有婴儿每12小时检测一次血清胆红素和血细胞比容。在治疗组中，12小时和24小时时分别下降了5.1%和7.8%，而对照组在12小时和24小时时分别升高了3.37%和2.9%。24小时后，治疗组的血清胆红素水平显著低于对照组（p<0.05）。治疗组无新生儿需要传统光疗，而对照组有4名婴儿需要（17.4%）。我们研究的结论是，小袋鼠系统在治疗新生儿非溶血性高胆红素血症方面是有用的，尽管其对更高胆红素水平的有效性仍有待测试。
