[Antimutagenic properties of substances containing beta-carotene].
作者信息
Shliankevich M A, Drize O B, Khabibulina V M, Sergeev A V, Privalova E G, Nikitiuk V G
出版信息
Vopr Med Khim. 1992 Nov-Dec;38(6):23-5.
PMID:1298121
Abstract
Two carotene-containing drugs (natural and artificial) were shown to decrease the rate of chromosomal aberrations, induced by cyclophosphane, in bone marrow cells of mice, daily ration of which contained 10-20 mg/kg of beta-carotene within 1-3 weeks. The rate of chromosomal aberrations induced was decreased 1.5-2-fold in various experiments. Artificial beta-carotene exhibited aftereffect within at least 3 days, while its protective effect was decreased about by 20% within 7 days after administration.
摘要
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