杀虫剂甲基对硫磷（Wofatox 50 EC）对雉鸡胚胎的致畸学检查。2. 生化研究。

Teratological examination of the insecticide methyl-parathion (Wofatox 50 EC) on pheasant embryos. 2. Biochemical study.

作者信息

Várnagy L

机构信息

Department of Agrochemical Hygiene, Georgikon Faculty of Agriculture, Pannon Agricultural University, Keszthely, Hungary.

出版信息

Acta Vet Hung. 1992;40(3):203-6.

Abstract

Fertile pheasant's eggs were treated with the insecticide Wofatox 50 EC (50% methyl-parathion) by injection technique on day 12 of the hatching period. Treatment consisted of inoculation of 0.1 ml of different concentrations of the insecticide into the air space of embryonated eggs. The following dose levels were employed: 0.00, 1.35, 13.5 and 135.0 mg/kg egg of active ingredient. Biochemical changes in the plasma were evaluated by micro (photometric) methods which rendered possible the determination of several blood plasma variables of the embryos. At the highest dose level applied, serum alkaline phosphatase (SAP) enzyme activity and inorganic P concentration of the treated embryos showed statistically differences (reduction) as compared to the control data. Macroscopic alterations were detected at necropsy.

摘要

在孵化期的第12天，采用注射技术用杀虫剂Wofatox 50 EC（50%甲基对硫磷）处理可育雉鸡蛋。处理方法是将0.1毫升不同浓度的杀虫剂接种到胚胎蛋的气室中。采用了以下剂量水平：活性成分0.00、1.35、13.5和135.0毫克/千克蛋。通过微量（光度）法评估血浆中的生化变化，该方法能够测定胚胎的几个血浆变量。在应用的最高剂量水平下，与对照数据相比，处理过的胚胎的血清碱性磷酸酶（SAP）酶活性和无机磷浓度显示出统计学差异（降低）。尸检时检测到宏观变化。

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