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[骨骼肌电刺激后的生化及功能变化]

[Biochemical and functional changes in skeletal muscles with electrostimulation].

作者信息

Hryhor'eiva V A, Medovar E N, Mieshkova L I, Radziieva'kyĭ O R, Hudz' P Z

出版信息

Ukr Biokhim Zh. 1975 May-Jun;47(3):362-9.

PMID:129899
Abstract

Electrostimulation of rabbit muscles for 18 days is accompanied by a disturbance in certain biochemical indices and functional state of the muscles. This is confirmed by a decrease in ATP content, intensity of Ca2+ uptake by the sarcoplasmatic reticulum fragments, by a drop in exitability (by the indices of rheobase and chronaxia) as well as by a change in the structure of muscular fibres components, motor axons, motor nerve endings and sciatic nerve stems. Less developed changes are observed when electrostimulation is performed for 5 days and twice for 5 days, including the period of rest. In this case the changes in Atp content and visual deviations in the muscles structure are absent and only the ability of the sarcoplasmatic reticulum fragments to Ca2+ uptake decreases insignificantly and the muscles excitability increases. Administration of ATP and simultaneous electrostimulation for 5 days normalize the disturbed Ca2+ uptake and preserve the higher excitability, that makes it possible to consider this regime of training to be the most acceptable.

摘要

对兔子肌肉进行18天的电刺激会伴随着某些生化指标和肌肉功能状态的紊乱。这通过三磷酸腺苷(ATP)含量的降低、肌浆网碎片对钙离子(Ca2+)摄取强度的下降、兴奋性的降低(以基强度和时值指标衡量)以及肌纤维成分、运动轴突、运动神经末梢和坐骨神经干结构的变化得到证实。当进行5天以及包括休息期在内的两次各5天的电刺激时,观察到的变化不太明显。在这种情况下,ATP含量没有变化,肌肉结构也没有明显偏差,只有肌浆网碎片对Ca2+的摄取能力略有下降,而肌肉兴奋性增加。给予ATP并同时进行5天的电刺激可使紊乱的Ca2+摄取恢复正常,并保持较高的兴奋性,这使得可以认为这种训练方式是最可接受的。

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