地中海贫血儿童和青少年的自发性血小板聚集

Spontaneous platelet aggregation in thalassemic children and adolescents.

作者信息

Laosombat V, Wongchanchailert M, Kenpitak K, Wisitpongpon C

机构信息

Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand 90112.

出版信息

Southeast Asian J Trop Med Public Health. 1992;23 Suppl 2:42-6.

PMID:1298992

Abstract

Spontaneous platelet aggregation was studied in 51 children and adolescents, comprising 30 nonsplenectomized thalassemic patients, 12 splenectomized thalassemic patients and 9 normal children. Spontaneous platelet aggregation was significantly increased in whole blood and platelet-rich plasma of splenectomized thalassemic patients but not in nonsplenectomized cases.

摘要

对51名儿童和青少年进行了自发性血小板聚集研究，其中包括30名未行脾切除术的地中海贫血患者、12名行脾切除术的地中海贫血患者和9名正常儿童。行脾切除术的地中海贫血患者的全血和富血小板血浆中的自发性血小板聚集显著增加，而未行脾切除术的患者则未出现这种情况。