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[冠状动脉内注射乙醇所致的病理性心肌改变及其机制]

[The pathologic myocardial change caused by intracoronary ethyl alcohol injection and its mechanism].

作者信息

Hua W

机构信息

Fu Wai Hospital, Beijing.

出版信息

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1992 Oct;14(5):371-3.

PMID:1299542
Abstract

Intracoronary chemical injection to ablate ventricular tachycardia is a new method. Through experiments in 22 dogs, we studied the pathologic change of the myocardium and its mechanism following intracoronary injection of 96% ethyl alcohol. All dogs receiving ethyl alcohol injection displayed myocardial necrosis, and most of them presented thrombus in the coronary branch. The pathologic change in the acute period may have resulted from direct ethyl alcohol damage, and that in the late period may have resulted from both direct damage and thrombus caused by arterial damage.

摘要

冠状动脉内化学注射消融室性心动过速是一种新方法。通过对22只犬进行实验,我们研究了冠状动脉内注射96%乙醇后心肌的病理变化及其机制。所有接受乙醇注射的犬均出现心肌坏死,且大多数犬的冠状动脉分支出现血栓。急性期的病理变化可能是由乙醇直接损伤所致,而后期的病理变化可能是由直接损伤和动脉损伤导致的血栓共同引起的。

相似文献

1
[The pathologic myocardial change caused by intracoronary ethyl alcohol injection and its mechanism].[冠状动脉内注射乙醇所致的病理性心肌改变及其机制]
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1992 Oct;14(5):371-3.
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[The experimental ablation of ventricular tachycardia in dogs with intracoronary ethyl alcohol injection].
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引用本文的文献

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A porcine model of ischemic heart failure produced by intracoronary injection of ethyl alcohol.通过冠状动脉内注射乙醇建立的缺血性心力衰竭猪模型。
Heart Vessels. 2011 May;26(3):342-8. doi: 10.1007/s00380-010-0022-3. Epub 2010 Oct 21.