Chen R Y
Department of Ophthalmology, First Teaching Hospital, Beijing Medical University.
Zhonghua Yan Ke Za Zhi. 1992 Jul;28(4):217-20.
The correlation of intraocular pressure (IOP) to optic nerve damages was studied in 17 patients of primary open angle glaucoma (POAG) and 24 patients of low tension glaucoma (LTG) both with monocular early glaucomatous damages. In the POAG group, the mean IOP was higher in the glaucomatous eye than in the other, while in the LTG group there was no significant IOP difference between the two eyes. Comparing the optic nerve damages in both groups, patients of POAG presented a concentrically enlarged cup with even disc rim and diffuse retinal nerve fiber layer defect (RNFLD), while patients of LTG exhibited a paracentrical cup with uneven disc rim and localized RNFLD. The results suggested that there could be different mechanisms of optic nerve damages in the two groups.
对17例原发性开角型青光眼(POAG)患者和24例低眼压性青光眼(LTG)患者进行了研究,这两组患者均为单眼早期青光眼性损害,研究眼内压(IOP)与视神经损害之间的相关性。在POAG组中,青光眼患眼的平均IOP高于另一只眼,而在LTG组中,两眼之间的IOP无显著差异。比较两组的视神经损害情况,POAG患者表现为杯盘比同心性增大,视盘边缘均匀,视网膜神经纤维层弥漫性缺损(RNFLD),而LTG患者表现为旁中心杯,视盘边缘不均匀,RNFLD局限。结果表明,两组视神经损害的机制可能不同。