Moeschler O, Ravussin P
Service d'Anesthésiologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Suisse.
Ann Fr Anesth Reanim. 1992;11(6):657-65. doi: 10.1016/s0750-7658(05)80786-5.
This paper reviews the principal aspects of the immediate management of patients suffering from spinal injury. An understanding of the pathophysiology of primary and secondary spinal cord injury enables appropriate initial care to be provided, thereby avoiding exacerbation and/or progressive deterioration of the lesion. It includes protective measures, restoration of vital functions to maintain adequate tissue perfusion and oxygenation, as well as pharmacological prevention of secondary injury. Protective measures include proper immobilisation of the spine with a semi-rigid collar and tape on a long backboard, or on vacuum mattress, taking great care to avoid deleterious in-line compression forces on the spinal column. The combination of cervical spine instability, a full stomach, unopposed vagal reflexes, hypoxia and hypercarbia makes airway management of these patients difficult. Tracheal intubation under fibroscopic control, with insertion of the tube only after topical anaesthesia of the airways under titrated intravenous sedation, offers safety and comfort to the patient. However, in cases of severe deterioration of vital functions, intubation must be performed without any delay at the site of the accident or in the emergency room. Three options are available: blind naso-tracheal intubation with spontaneous breathing, modified rapid sequence induction with orotracheal intubation under double protection, and immediate surgical airway if these techniques fail. Patients with cervical spine injury may demonstrate severe hypotension requiring sympathomimetic agents and careful fluid loading to avoid pulmonary oedema. To prevent aggravation of the spinal cord injury by systemic factors, the goal of initial resuscitation is to restore an adequate perfusion pressure of at least 60 mmHg, a PaO2 > 100 mmHg, and to keep PaCO2 below 45 mmHg.(ABSTRACT TRUNCATED AT 250 WORDS)
本文综述了脊髓损伤患者即刻处理的主要方面。了解原发性和继发性脊髓损伤的病理生理学有助于提供恰当的初始治疗,从而避免损伤加重和/或病情进行性恶化。这包括保护措施、恢复重要功能以维持充足的组织灌注和氧合,以及药物预防继发性损伤。保护措施包括使用半刚性颈托和胶带将脊柱妥善固定在长背板或真空床垫上,要格外小心避免对脊柱产生有害的轴向压缩力。颈椎不稳定、饱胃、无对抗的迷走反射、缺氧和高碳酸血症共同导致这些患者的气道管理困难。在纤维喉镜引导下气管插管,仅在气道局部麻醉并给予滴定的静脉镇静后插入气管导管,可为患者提供安全和舒适。然而,在重要功能严重恶化的情况下,必须在事故现场或急诊室立即进行插管,不得延误。有三种选择:自主呼吸下的盲鼻气管插管、双重保护下经口气管插管的改良快速顺序诱导,以及这些技术失败时立即进行手术气道建立。颈椎损伤患者可能出现严重低血压,需要使用拟交感神经药并谨慎补液以避免肺水肿。为防止全身因素加重脊髓损伤,初始复苏的目标是恢复至少60 mmHg的充足灌注压、PaO2 > 100 mmHg,并使PaCO2低于45 mmHg。(摘要截断于250字)