Bofinger E
Department of Mathematics, Statistics, and Computing Science, University of New England, Armidale, N.S.W., Australia.
J Biopharm Stat. 1992;2(2):181-8. doi: 10.1080/10543409208835038.
An argument, based on expanded confidence intervals, is given for always performing one-sided tests. However, if goals are not one-sided and "follow-up" inferences are required, then the usual two-sided confidence intervals (corresponding to two-sided tests) are generally appropriate. When equivalence testing is required (the goal being to show that treatments are "not too different"), expanded confidence intervals are more efficient than Westlake's symmetrical confidence intervals.
基于扩展置信区间给出了始终进行单侧检验的论据。然而,如果目标不是单侧的且需要进行“后续”推断,那么通常的双侧置信区间(对应双侧检验)一般是合适的。当需要进行等效性检验时(目标是表明治疗方法“差异不大”),扩展置信区间比韦斯特莱克对称置信区间更有效。