Ueki T, Takeo G, Kinoshita I, Tsujihata M, Nagataki S
First Department of Internal Medicine, Nagasaki University School of Medicine.
Rinsho Shinkeigaku. 1992 Sep;32(9):1028-31.
A 68-year-old woman was admitted to Nagasaki University Hospital complaining of gait disturbance. She had suffered from hemifacial spasm since the age of 56 and had undergone neurovascular decompression for the spasm in another hospital five years before admission. At surgery, the vertebral and posterior inferior cerebellar arteries had been separated from the facial nerve with cotton string and attached to the clivus with alpha-cyanoacrylate monomer. Although the hemifacial spasm had improved postoperatively, the patient had suffered from gait disturbance and headache for two months after surgery, and hearing disturbance and hemifacial palsy on the same side as the hemifacial spasm for seven months after surgery. At the time of the present admission, contrast-enhanced CT scan revealed a mass at the left cerebello-pontine angle. In the T1-weighted inversion recovery sequence of MRI, the mass showed a slightly lower intensity than that of surrounding tissues. In the T2-weighted spin echo sequence of MRI, it showed a heterogenously low intensity with some high intensity spots. We diagnosed this mass as a foreign-body granuloma and treated it with dexamethasone injected intramuscularly. Edema decreased around the granuloma, and her gait disturbance improved markedly. But the hearing disturbance and hemifacial palsy did not improve at all, indicating that these two symptoms might not be caused only by brain edema but also by direct damage due to granuloma or inflammation. We thought that the steroid hormone elicited good results in the treatment of inoperable foreign-body granuloma.
一名68岁女性因步态障碍入住长崎大学医院。她自56岁起患有半面痉挛,入院前五年在另一家医院接受了针对该痉挛的神经血管减压手术。手术中,椎动脉和小脑后下动脉已用棉线与面神经分离,并用α-氰基丙烯酸酯单体附着于斜坡。尽管术后半面痉挛有所改善,但患者术后两个月出现步态障碍和头痛,术后七个月出现与半面痉挛同侧的听力障碍和面瘫。本次入院时,增强CT扫描显示左侧桥小脑角有一肿块。在MRI的T1加权反转恢复序列中,肿块的信号强度略低于周围组织。在MRI的T2加权自旋回波序列中,它显示为不均匀的低信号,伴有一些高信号点。我们将此肿块诊断为异物肉芽肿,并用肌肉注射地塞米松进行治疗。肉芽肿周围的水肿减轻,她的步态障碍明显改善。但听力障碍和面瘫完全没有改善,这表明这两种症状可能不仅由脑水肿引起,还可能由肉芽肿或炎症的直接损伤所致。我们认为类固醇激素在治疗无法手术的异物肉芽肿方面取得了良好效果。