[雄性C57BL/6小鼠生殖功能障碍期间Lewis肺癌的生长和转移特性]
[The growth and metastatic characteristics of Lewis lung carcinoma during reproductive dysfunction in male C57BL/6 mice].
作者信息
Mikhaĭlevskaia L L, Galochkina Z I, Koroleva A M, Shumova S L, Kinzirskiĭ A S
出版信息
Vopr Onkol. 1992;38(9):1090-6.
PMID:1300823
Abstract
Results of a study of the pattern of spontaneous dissemination of Lewis lung carcinoma in male mice with reproductive system dysfunction showed that removal of the gonads followed by substitution treatment with testosterone failed to influence tumor metastatic potential. The data suggested that the androgen lacked a modulating effect on growth and dissemination of Lewis lung carcinoma.
摘要
一项关于Lewis肺癌在具有生殖系统功能障碍的雄性小鼠中自发扩散模式的研究结果表明，切除性腺后用睾酮替代治疗未能影响肿瘤转移潜能。数据表明，雄激素对Lewis肺癌的生长和扩散缺乏调节作用。
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