Kirkegaard Nielsen H, May O
Department of Anaesthesia, Esbjerg Central Hospital, Denmark.
Acta Anaesthesiol Belg. 1992;43(4):253-7.
Double burst stimulation (DBS) is a new nerve stimulation pattern introduced to facilitate tactile evaluation of recovery from neuromuscular blockade. DBS consists of two bursts of high frequency stimulations separated by a short time interval. The relationships between DBS, post-tetanic count (PTC) and train-of-four (TOF) on the evoked twitch response was investigated in 16 surgical patients and 7 intensive care patients given atracurium for muscle relaxation. A significant correlation between the twitch height of the first response to DBS and the number of post-tetanic responses was demonstrated when PTC was more than five (r = 0.47, p < 0.0003). When the first twitch of TOF was still not measurable, the first twitch of DBS ranged from 0 to 20% of the TOF-control twitch height. Furthermore the DBS ratio was significantly correlated to the TOF ratio (r = 0.92-0.96, p < 0.0002). It is concluded that DBS not only can be used for monitoring of recovery from neuromuscular blockade, but also for monitoring of intense degrees of neuromuscular blockade.
双重爆发刺激（DBS）是一种新引入的神经刺激模式，用于促进对神经肌肉阻滞恢复情况的触觉评估。DBS由两个高频刺激串组成，中间间隔较短时间。在16例接受阿曲库铵肌肉松弛的外科患者和7例重症监护患者中，研究了DBS、强直后计数（PTC）和四个成串刺激（TOF）与诱发抽搐反应之间的关系。当PTC大于5时，DBS首次反应的抽搐高度与强直后反应次数之间存在显著相关性（r = 0.47，p < 0.0003）。当TOF的首次抽搐仍无法测量时，DBS的首次抽搐幅度为TOF对照抽搐高度的0%至20%。此外，DBS比率与TOF比率显著相关（r = 0.92 - 0.96，p < 0.0002）。结论是，DBS不仅可用于监测神经肌肉阻滞的恢复情况，还可用于监测神经肌肉阻滞的深度。
