Diall O, Touré O B, Diarra B, Sanogo Y
Laboratoire central vétérinaire du Mali, Bamako.
Rev Elev Med Vet Pays Trop. 1992;45(2):155-61.
This work aims at contributing to the knowledge of trypanosomiasis epidemiology in calves of trypanotolerant breeds and at defining an appropriate treatment to improve the survival of such calves in a tsetse infested area. The first study was a parasitological survey of 100 calves from the day of birth to the age of one year. According to the results of this survey, the period from birth to three months is a "critical" moment in the life of the calves, due to a high infection rate and mortality related to trypanosomiasis. The purpose of the second study was to investigate the possible interference of early trypanocidal treatments with the further expression of trypanotolerance. For this purpose three groups of over one-year old animals were established. The groups had different trypanosomiasis history due to the different treatments they had undergone during their first year of life. All the animals had been exposed to trypanosomiasis without treatment and followed up parasitologically and clinically during the second year. The results showed no interference of early trypanocidal treatments (including preventive ones) with the expression of resistance in potentially trypanotolerant animals.
这项工作旨在增进对锥虫耐受品种犊牛锥虫病流行病学的了解，并确定一种合适的治疗方法，以提高此类犊牛在采采蝇滋生地区的存活率。第一项研究是对100头犊牛从出生到一岁进行的寄生虫学调查。根据这项调查的结果，从出生到三个月这段时间是犊牛生命中的一个“关键”时刻，因为与锥虫病相关的感染率和死亡率很高。第二项研究的目的是调查早期杀锥虫治疗对锥虫耐受性进一步表达的可能干扰。为此，建立了三组一岁以上的动物。由于它们在生命的第一年接受了不同的治疗，这些组有不同的锥虫病病史。所有动物都未经治疗接触过锥虫病，并在第二年进行了寄生虫学和临床随访。结果表明，早期杀锥虫治疗（包括预防性治疗）对潜在锥虫耐受动物的抗性表达没有干扰。
