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围手术期疼痛的药物治疗

[Drug treatment of perioperative pain].

作者信息

Bazin J E, Picard P

机构信息

Département d'Anesthésie-Réanimation, Hôpital Gabriel Montpied, Clermont-Ferrand.

出版信息

Therapie. 1992 Nov;47(6):481-4.

PMID:1301640
Abstract

Several drugs and techniques have been developed to improve the quality of post operative analgesia. Opiates are always the first intention drugs, specially with new molecules (buprenorphine, nalbuphine ...). Paracetamol and non-steroid anti-inflammatory drugs can be efficacious in the post operative period alone or as adjuvants. The alpha 2 adrenergic agonists use must be specify. The patient auto-controlled administration and the transdermal administration of opiates are useful techniques to provide effective analgesia with optimal safety.

摘要

已经开发了几种药物和技术来提高术后镇痛的质量。阿片类药物一直是首选药物,特别是新的分子(丁丙诺啡、纳布啡……)。对乙酰氨基酚和非甾体抗炎药单独或作为辅助药物在术后阶段可能有效。α2肾上腺素能激动剂的使用必须明确说明。患者自控给药和阿片类药物的透皮给药是提供有效镇痛且安全性最佳的有用技术。

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