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[蒙古地区脑膜炎球菌感染的演变]

[The evolution of meningococcal infection in Mongolia].

作者信息

Tsénd N, Enkhbold B, Deviatkina N P, Martynov Iu V, Demina A A

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1992(11-12):27-30.

PMID:1301657
Abstract

On the basis of the generalization and analysis of the results of bacteriological and immunological investigations the epidemic process of meningococcal infection (MI) in Mongolia was found to undergo definite changes during the last 20 years. Group A meningococci prevailing in the etiology of MI were replaced by strains belonging to group B affecting mainly young children (aged up to 3 years). MI morbidity rate caused by group B meningococci was found to be higher in Mongolia than in other countries of the world. These data substantiate the necessity of using more effective remedies for the control of this infection and, in particular, specific immunization with vaccines against group B meningococci; profound study of the properties of the circulating meningococcal strains is to be carried out.

摘要

在对细菌学和免疫学调查结果进行综合分析的基础上,发现蒙古的脑膜炎球菌感染(MI)流行过程在过去20年中发生了明显变化。MI病因中占主导的A群脑膜炎球菌被主要感染幼儿(3岁及以下)的B群菌株所取代。研究发现,蒙古由B群脑膜炎球菌引起的MI发病率高于世界其他国家。这些数据证实了使用更有效药物控制这种感染的必要性,特别是针对B群脑膜炎球菌疫苗的特异性免疫接种;需要对流行的脑膜炎球菌菌株特性进行深入研究。

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