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[有组织群体中脑膜炎球菌感染流行过程发展机制的特征]

[Characteristics of the mechanism of the development of the epidemic process in meningococcal infection in organized collectives].

作者信息

Efimov E I

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1988 Aug(8):56-60.

PMID:3143208
Abstract

The specific features of the epidemiology of meningococcal infection in organized groups have been established after comprehensive (epidemiological, microbiological and immunological) studies, evaluated from the viewpoint of the law of the autoregulation of the epidemic process. The studies have revealed the phenomenon of the adaptive biological variability of meningococci with their prolonged reservation due to the transformation of typical bacterial forms of meningococci characterized by strict serogroup specificity and typical fermentative activity into serologically and biochemically undifferentiated forms, capable of prolonged persistence in human populations. The model demonstrating the development of the epidemic process in meningococcal infection in an organized group has been worked out.

摘要

在从流行过程的自动调节规律的角度进行综合(流行病学、微生物学和免疫学)研究之后,已确定了有组织群体中脑膜炎球菌感染流行病学的具体特征。这些研究揭示了脑膜炎球菌适应性生物变异性的现象,即由于典型的具有严格血清群特异性和典型发酵活性的脑膜炎球菌细菌形式转变为血清学和生化上无差异的形式,它们能够在人群中长时间留存。已经建立了一个模型,用以展示有组织群体中脑膜炎球菌感染流行过程的发展情况。

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