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[为弗留利-威尼斯朱利亚地区酗酒者提供的上呼吸道和消化系统肿瘤早期诊断项目]

[The program for early diagnosis of the upper respiratory tract and digestive system neoplasms offered to alcoholics in the region of Friuli-Venice Giulia].

作者信息

Barra S, Mattotti M, Bertos G, Barzan L

机构信息

Servizio di Epidemiologia e Direzione Sanitaria, Centro di Riferimento Oncologico, Aviano.

出版信息

Acta Otorhinolaryngol Ital. 1992 Jul-Aug;12(4):337-44.

PMID:1301670
Abstract

The present study deals with data from an on-going collaborative programme of early diagnosis for upper aero-digestive tract tumors established since 1990 by three ENT Departments of the Friuli-Venezia Giulia Region, Northeastern Italy. The aim of the study was firstly to evaluate the socio-economic characteristics and clinical features of alcoholics in treatment who were offered a free ENT check-up, and secondly to test the feasibility of this type of referral of high-risk patients from non-medical associations to the ENT specialist. A total of 683 patients, of which 151 (78%) were males and 151 (22%) were females, underwent ENT examination. About 25% of the patients were symptomatic, the most frequent symptom being dysphonia (50%) followed by cough (19%), while dyspnoea, dysphagia and pain were present in about 5% of the patients. Other than nearly 50% negative findings, ENT examination revealed a high percentage of inflammatory lesions (30%) of the upper aero-digestive tract. In 37 patients (6%) a precancerous lesion was found and in four cases an histologically confirmed tumor was diagnosed. Although the present study cannot be considered a complete screening, it did clearly evaluate the amount of response given by this high-risk population of alcoholics in treatment to the offer of an ENT examination and gives encouraging results concerning the feasibility of early diagnosis programmes for upper aero-digestive tract tumors which do not follow the normal routine of a sanitary referral by a general practitioner.

摘要

本研究涉及自1990年以来由意大利东北部弗留利-威尼斯朱利亚大区的三个耳鼻喉科建立的上呼吸消化道肿瘤早期诊断合作项目的数据。该研究的目的,一是评估接受免费耳鼻喉科检查的正在接受治疗的酗酒者的社会经济特征和临床特征,二是测试将高危患者从非医疗协会转诊至耳鼻喉科专家这种方式的可行性。共有683名患者接受了耳鼻喉科检查,其中151名(78%)为男性,151名(22%)为女性。约25%的患者有症状,最常见的症状是声音嘶哑(50%),其次是咳嗽(19%),而呼吸困难、吞咽困难和疼痛在约5%的患者中出现。除了近50%的阴性结果外,耳鼻喉科检查显示上呼吸消化道有较高比例(30%)的炎性病变。在37名患者(6%)中发现了癌前病变,4例经组织学确诊为肿瘤。尽管本研究不能被视为一次完整的筛查,但它确实清楚地评估了这一接受治疗的高危酗酒人群对耳鼻喉科检查提议的反应程度,并就不遵循全科医生常规卫生转诊程序的上呼吸消化道肿瘤早期诊断项目的可行性给出了令人鼓舞的结果。

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