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[关于体外培养的正常和肿瘤植物组织行为的放射生物学研究]

[Radiobiological studies on the behavior of normal and tumorous plant tissues cultivated in vitro].

作者信息

Jonard R, Ravelomanana D

出版信息

C R Seances Soc Biol Fil. 1975;169(3 Suppl):759-65.

PMID:130188
Abstract

Vegetable tumoral tissue are more radiosensitive than the homologous normal tissue. Tumoral tissue are more stimulated by yeast extract and yeast s-ARN than normal tissue. Yeast extracts and s-RNA extracts from yeast also restore more the growth of tumorous tissue than normal tissue, which were subjected to gamma radiation from 60Co. A mixture of mononucleotides obtained from fractionated s-RNA has the same stimulatory effect. It is suggested that the active principle from yeast and s-RNA is a cytokinin like substance, which have been detected in yeast extract and in soluble ribonucleic acid from yeast.

摘要

蔬菜肿瘤组织比同源正常组织对辐射更敏感。肿瘤组织比正常组织对酵母提取物和酵母s-ARN的刺激更敏感。酵母提取物和酵母s-RNA提取物对经60Coγ射线照射的肿瘤组织生长的恢复作用也比正常组织更强。从分级分离的s-RNA中获得的单核苷酸混合物具有相同的刺激作用。有人认为,酵母和s-RNA中的活性成分是一种细胞分裂素样物质,已在酵母提取物和酵母可溶性核糖核酸中检测到。

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