Bastos Freitas L, Pinheiro Fernandes C, Attström R
Department of Periodontology and Prosthetic Dentistry, Faculty of Odontology, Lund University, Malmö, Sweden.
Braz Dent J. 1992;3(1):17-23.
The aim of this study was to determine the effect of 1% chlorhexidine gel delivered with toothpicks on interproximal dental plaque. Seven follow-up patients participated in two treatment periods of 1 week each, separated by a normal oral hygiene period of one week. The study had double-blind design. The plaque index by Silness and Löe (Acta Odontol Scand 22: 121-135, 1964) was scored on mesial, distal, buccal and lingual surfaces of each tooth after plaque disclosure, with an aqueous solution of erythrosine and the measurements were performed by the same examiner, at the initial visit and at the end of every experimental week. The ability to use toothpicks was checked and upgraded to the individual need. The participants were instructed to carry out their normal oral hygiene procedures, with placebo gel or 1% chlorhexidine gel delivered interproximally with toothpicks once daily. No significant differences in the measurement of plaque were noted between placebo gel and 1% chlorhexidine gel at interproximal areas. After treatment with 1% chlorhexidine gel, the mean distribution of plaque score 0 was increased significantly (P < 0.05), from 30.7 sites (52%) to 42 sites (71.1%) when all sites are taken into account and compared to the placebo period. 1% Chlorhexidine gel delivered by toothpick on interproximal areas had a limited effect on reduction of dental plaque.
本研究的目的是确定用牙签递送1%洗必泰凝胶对牙邻面菌斑的影响。七名随访患者参与了两个为期1周的治疗期，中间间隔1周的正常口腔卫生期。该研究采用双盲设计。在菌斑染色后，使用赤藓红水溶液，由同一名检查者在初次就诊时以及每个实验周结束时，对每颗牙齿的近中、远中、颊侧和舌侧表面按照Silness和Löe的菌斑指数（《斯堪的纳维亚牙科学报》22: 121 - 135, 1964）进行评分。检查并根据个人需求提升使用牙签的能力。参与者被指示进行正常的口腔卫生程序，每天一次用牙签在牙邻面递送安慰剂凝胶或1%洗必泰凝胶。在牙邻面区域，安慰剂凝胶和1%洗必泰凝胶之间在菌斑测量方面未发现显著差异。在使用1%洗必泰凝胶治疗后，当考虑所有部位并与安慰剂期相比时，菌斑评分为0的平均分布显著增加（P < 0.05），从30.7个部位（52%）增加到42个部位（71.1%）。用牙签递送1%洗必泰凝胶对减少牙邻面菌斑的效果有限。
