Rodríguez-Balderrama I, Udaeta-Mora E, Cardiel-Marmolejo L E, Vargas-Quintal F, Fernández-Carrocera L
División de Pediatria, Instituto Nacional de Perinatologia, México, D.F.
Bol Med Hosp Infant Mex. 1992 Jan;49(1):26-31.
One hundred and five very low birth weight neonates, selected through convenience sampling during 1989, were subdivided into those who received mechanical ventilation (MCV) and those who did not receive mechanical ventilation (W/O MCV) and later analyzed. The maternal morbidity in both groups were very similar; 66 of the cases were placed in group MCV and 39 in the W/O MCV. There were differences in birth weight, gestational age, severe asphyxia and hospital stay in the patients with MCV. The neonatal morbidity (SDR, intraventricular hemorrhaging, bronchopulmonary dysplasia, etc.) was more frequently seen in this group. The global mortality was 47%, all of the cases were from the ventilated group. The ventilated patients who died were in the hospital a lesser number of days and had a lesser frequency of prenatal control. We conclude that low weight neonates who require mechanical respiratory assistance have a greater risk of morbidity and mortality. The lesser weight and gestational age, the greater the risk. A group of neonates will have a lesser capacity to synthesize phospholipids and therefore a greater risk of dying. Physicians should be more attentive to the complications related to ventilated low-weight premature neonates.
1989年通过便利抽样选取的105例极低出生体重儿被分为接受机械通气的患儿（MCV组）和未接受机械通气的患儿（非MCV组），随后进行分析。两组产妇的发病率非常相似；66例被归入MCV组，39例被归入非MCV组。MCV组患儿在出生体重、胎龄、重度窒息和住院时间方面存在差异。该组新生儿发病率（如SDR、脑室内出血、支气管肺发育不良等）更为常见。总体死亡率为47%，所有死亡病例均来自机械通气组。死亡的机械通气患儿住院天数较少，产前检查次数也较少。我们得出结论，需要机械呼吸支持的低体重儿发病和死亡风险更高。体重和胎龄越小，风险越大。一组新生儿合成磷脂的能力较低，因此死亡风险更高。医生应更加关注与机械通气的低体重早产儿相关的并发症。
