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对两匹患有联合免疫缺陷的马驹进行免疫治疗,导致移植物抗宿主反应。

Immunotherapy in two foals with combined immunodeficiency, resulting in graft versus host reaction.

作者信息

Ardans A A, Trommershausen-Smith A, Osburn B I, Mayhew I G, Trees C, Park M I, Sawyer M, Stabenfeldt G H

出版信息

J Am Vet Med Assoc. 1977 Jan 15;170(2):167-75.

PMID:13055
Abstract

Immunotherapy was attempted in 2 Arabian foals with combined immunodeficiency. One foal was given a transplant of bone marrow from a selected full sibling, and 1 foal was given a fetal thymus transplant. Both foals died. Genetic evidence was obtained for survival of the transplanted tissues in both cases; however, a graft versus host reaction developed in the foal given the fetal thymus transplant.

摘要

对2匹患有联合免疫缺陷的阿拉伯马驹尝试进行免疫治疗。1匹马驹接受了来自选定的同窝全同胞的骨髓移植,另1匹马驹接受了胎儿胸腺移植。两匹马驹均死亡。在这两个病例中均获得了移植组织存活的基因证据;然而,接受胎儿胸腺移植的马驹发生了移植物抗宿主反应。

相似文献

3
Immunologic reconstitution of foals with combined immunodeficiency.
Vet Immunol Immunopathol. 1987 Dec;17(1-4):495-508. doi: 10.1016/0165-2427(87)90165-6.

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