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丙种球蛋白;预防脊髓灰质炎的可获得情况

Gamma globulin; status of availability for prevention of poliomyelitis.

作者信息

HALVERSON W L, DRAKE R M

出版信息

Calif Med. 1953 Jul;79(1):1-5.

PMID:13059636
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1521754/
Abstract

A limited and temporary preventive effect has been noted for gamma globulin used under certain conditions. There is available a supply of gamma globulin which is inadequate to meet the demand with the methods of use indicated in the light of present knowledge. All supplies of gamma globulin have been placed under the responsibility of the Office of Defense Mobilization. Supplies allocated to the state of California are being made available to physicians through their local health departments on the basis of past and current incidence of poliomyelitis for use in protecting persons in household contact with patients with diagnosed cases. The most effective use of California's allocation of this material can be expected to prevent or modify approximately 40 cases on the basis of the past five-year experience (1947-1951). Parents, physicians and health officials must know the facts and cooperate to make the best of a difficult situation.

摘要

在某些条件下使用的丙种球蛋白已显示出有限的临时预防效果。现有丙种球蛋白的供应量,按照目前所知的使用方法,不足以满足需求。所有丙种球蛋白的供应均由国防动员办公室负责。分配给加利福尼亚州的丙种球蛋白,正通过当地卫生部门提供给医生,分配依据是脊髓灰质炎过去和当前的发病率,用于保护与确诊病例的患者有家庭接触的人员。根据过去五年(1947 - 1951年)的经验,预计加利福尼亚州对这种物资的分配若得到最有效利用,可预防或减轻约40例病例。家长、医生和卫生官员必须了解实际情况并合作,以便在困难的情况下做到最好。

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Gamma globulin; status of availability for prevention of poliomyelitis.丙种球蛋白;预防脊髓灰质炎的可获得情况
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本文引用的文献

1
Poliomyelitis in pregnancy.妊娠期脊髓灰质炎
Am J Hyg. 1952 Jan;55(1):127-39. doi: 10.1093/oxfordjournals.aje.a119501.
2
Further studies on oral administration of living poliomyelitis virus to human subjects.
Proc Soc Exp Biol Med. 1953 Feb;82(2):277-80. doi: 10.3181/00379727-82-20091.
3
Evaluation of Red Cross gamma globulin as a prophylactic agent for poliomyelitis. IV. Final report of results based on clinical diagnoses.红十字会丙种球蛋白作为脊髓灰质炎预防剂的评估。IV. 基于临床诊断的最终结果报告。
J Am Med Assoc. 1953 Apr 11;151(15):1272-85.
4
Studies in human subjects on active immunization against poliomyelitis. I. A preliminary report of experiments in progress.关于人类脊髓灰质炎主动免疫的研究。一、正在进行的实验的初步报告。
J Am Med Assoc. 1953 Mar 28;151(13):1081-98.
5
Distribution of poliomyelitis virus in the epidemic community.脊髓灰质炎病毒在流行社区中的分布情况。
Trans Assoc Am Physicians. 1952;65:176-83.
6
Evaluation of Red Cross gamma globulin as a prophylactic agent for poliomyelitis. 3. Preliminary report of results based on clinical diagnosis.红十字会丙种球蛋白作为脊髓灰质炎预防剂的评估。3. 基于临床诊断的初步结果报告。
J Am Med Assoc. 1952 Oct 25;150(8):757-60. doi: 10.1001/jama.1952.03680080019003.
7
Evaluation of Red Cross gamma globulin as a prophylactic agent for poliomyelitis. 2. Conduct and early follow-up of 1952 Texas and Iowa-Nebraska studies.红十字会γ球蛋白作为脊髓灰质炎预防剂的评估。2. 1952年德克萨斯州及爱荷华 - 内布拉斯加州研究的开展与早期随访。
J Am Med Assoc. 1952 Oct 25;150(8):750-6. doi: 10.1001/jama.1952.03680080012002.
8
Evaluation of Red Cross gamma globulin as a prophylactic agent for poliomyelitis. I. Plan of controlled field tests and results of 1951 pilot study in Utah.红十字会γ球蛋白作为脊髓灰质炎预防剂的评估。I. 对照现场试验计划及1951年在犹他州进行的初步研究结果。
J Am Med Assoc. 1952 Oct 25;150(8):739-49. doi: 10.1001/jama.1952.03680080001001.