Chuah M I, Au C
Department of Anatomy, Chinese University of Hong Kong, Shatin, N.T.
Dev Neurosci. 1992;14(5-6):357-61. doi: 10.1159/000111683.
Olfactory tissues from human fetuses (17.5-28 weeks of gestation) were stained by immunofluorescence for neural cell adhesion molecules (N-CAMs). Staining for N-CAMs was most prominent in the olfactory nerve bundles in the lamina propria, while in the olfactory epithelium, it was present on the olfactory receptor neurons and globose basal cells. The basal cells proper and supporting cells lacked N-CAMs. In the olfactory bulb, only the olfactory nerve and glomerular layers showed moderate labeling for N-CAMs. Western blot analysis showed that the N-CAMs of the fetal human primary olfactory pathway consisted of three molecular isoforms, N-CAM180, N-CAM140 and N-CAM120.
对人类胎儿（妊娠17.5 - 28周）的嗅觉组织进行免疫荧光染色，以检测神经细胞黏附分子（N-CAMs）。N-CAMs染色在固有层的嗅神经束中最为显著，而在嗅上皮中，它存在于嗅觉受体神经元和球状基底细胞上。真正的基底细胞和支持细胞缺乏N-CAMs。在嗅球中，只有嗅神经层和肾小球层显示出中等程度的N-CAMs标记。蛋白质印迹分析表明，胎儿人类初级嗅觉通路的N-CAMs由三种分子异构体组成，即N-CAM180、N-CAM140和N-CAM120。
