Eulry F, Chevalier X, Crozes P, Lechevalier D, Magnin J, Prudat M, Patoz P, Larget-Piet B
Service de Rhumatologie, Hôpital d'Instruction des Armées Begin, Saint-Mandé.
Rev Rhum Mal Osteoartic. 1992 Nov 30;59(11):721-7.
Plasma levels of cholesterol, triglyceride, HDL-cholesterol, and apolipoproteins A1 and B were assayed in ninety patients (sixty-four male and twenty-six female) with reflex sympathetic dystrophy and in ninety controls matched for age, sex, and body mass index (BMI). No significant differences were found between the two groups for the proportions of patients with increased plasma cholesterol levels (6.6% versus 4.4%) or increased plasma triglyceride levels (40% versus 30%), as defined by Turpin's age and sex-specific criteria, or for mean values of these parameters. In the 38 patients with reflex sympathetic dystrophy of less than 3.5 months duration, plasma triglyceride levels were significantly higher than in the 38 matched controls (1.24 + 0.57 g/l versus 1.02 +/- 0.91; p = 0.04). In patients (n = 52) with disease of more than four months duration (range 4-39), plasma triglyceride levels were similar in the two groups. Lipidemia was similar in patients and controls regardless of age, sex, topography of the disease, clinical manifestations, and whether or not the disease was due to an injury. This study, in contrast to previous reports, failed to disclose an association between reflex sympathetic dystrophy and hyperlipidemia. Transient hypertriglyceridemia may occur during the first 3 1/2 months of the disease as a result of initial immobilization.
对90例(64例男性和26例女性)反射性交感神经营养不良患者以及90例年龄、性别和体重指数(BMI)相匹配的对照者的血浆胆固醇、甘油三酯、高密度脂蛋白胆固醇以及载脂蛋白A1和B水平进行了检测。根据Turpin的年龄和性别特异性标准,两组之间血浆胆固醇水平升高的患者比例(6.6%对4.4%)或血浆甘油三酯水平升高的患者比例(40%对30%),以及这些参数的平均值均无显著差异。在病程小于3.5个月的38例反射性交感神经营养不良患者中,血浆甘油三酯水平显著高于38例匹配的对照者(1.24 + 0.57g/L对1.02 +/- 0.91;p = 0.04)。在病程超过4个月(范围4 - 39个月)的患者(n = 52)中,两组的血浆甘油三酯水平相似。无论年龄、性别、疾病部位、临床表现以及疾病是否由损伤引起,患者和对照者的血脂情况相似。与之前的报告相反,本研究未能揭示反射性交感神经营养不良与高脂血症之间的关联。疾病最初3个半月期间由于开始制动可能会出现短暂的高甘油三酯血症。