Schenone H, Contreras M, Salinas P, Sandoval L, Pérez-Olea J, Rojas A, Solís F, Villarroel F
Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad de Chile, Santiago.
Bol Chil Parasitol. 1992 Jul-Dec;47(3-4):84-5.
To each of 11,161 randomly taken people from urban and peri-urban localities of the first seven regions of Chile (geographic area of distribution of Chagas' disease in the country), with negative serology for Chagas' disease, an indirect hemagglutination test (IHAT) for toxoplasmosis and an EKG were practiced. The IHAT for toxoplasmosis resulted positive in 3,519 individuals (31.5%). The EKG showed alterations in 10.9% of the IHAT positive individuals and in 7.9% of the IHAT negative ones. This difference between the proportion of altered EKG in IHAT positive people and altered EKG in those with negative IHAT is statistically significative with p < 0.001. These results suggest the convenience of considering toxoplasmosis as a cause of chronic myocardiopathy in epidemiological studies on Chagas' disease, since not discard the presence of Toxoplasma gondii infection should overvaluete the magnitude of the impact of Trypanosoma cruzi in the genesis of such a myocardiopathy.
从智利前七个地区的城市和城郊地区随机抽取了11161名查加斯病血清学检测呈阴性的人，对他们进行了弓形虫病间接血凝试验（IHAT）和心电图检查。弓形虫病的间接血凝试验结果显示，3519人（31.5%）呈阳性。心电图显示，间接血凝试验阳性者中有10.9%出现异常，间接血凝试验阴性者中有7.9%出现异常。间接血凝试验阳性者中异常心电图比例与间接血凝试验阴性者中异常心电图比例之间的差异具有统计学意义，p<0.001。这些结果表明，在关于查加斯病的流行病学研究中，将弓形虫病视为慢性心肌病病因是合适的，因为不排除弓形虫感染的存在可能会高估克氏锥虫在这种心肌病发生过程中的影响程度。
