Fu X B
Trauma Center of Postgraduate Medical College, 304th Hospital, People's Liberation Army, Beijing.
Zhonghua Wai Ke Za Zhi. 1992 Sep;30(9):563-6, 573.
The effects of shock and reperfusion on multiple organ function in gunshot canine model were studied. The results showed that organ function damage even failure of the lung, liver and kidney occurred 24 hours after wound. In some dogs bacterial translocation and increase of lipid peroxidation (LPO) were also found. The experimental findings suggested that the activated free radical system and bacterial translocation may be the underlying pathogenesis of multiple organ injuries and failure. It is possible to establish a model for studying multiple organ failure on this experimental condition.
研究了枪击犬模型中休克和再灌注对多器官功能的影响。结果显示，受伤24小时后出现器官功能损害，甚至肺、肝和肾衰竭。在一些犬中还发现了细菌移位和脂质过氧化（LPO）增加。实验结果表明，激活的自由基系统和细菌移位可能是多器官损伤和衰竭的潜在发病机制。在这种实验条件下有可能建立一个研究多器官衰竭的模型。
