Caruso A, Cutuli V M, De Bernardis E, Attaguile G, Amico-Roxas M
Institute of Pharmacology, University of Catania Medical School, Italy.
Drugs Exp Clin Res. 1992;18(11-12):481-5.
In this study the pharmacological evaluation of MED-15, a non-acidic prodrug of tolmetin, is described. After oral administration the new compound shows a marked anti-inflammatory activity similar to that of tolmetin, but with minor ulcerogenic action and lower acute toxicity.
