Pharmacological properties and toxicology of MED-15, a prodrug of tolmetin.
作者信息
Caruso A, Cutuli V M, De Bernardis E, Attaguile G, Amico-Roxas M
机构信息
Institute of Pharmacology, University of Catania Medical School, Italy.
出版信息
Drugs Exp Clin Res. 1992;18(11-12):481-5.
PMID:1308474
Abstract
In this study the pharmacological evaluation of MED-15, a non-acidic prodrug of tolmetin, is described. After oral administration the new compound shows a marked anti-inflammatory activity similar to that of tolmetin, but with minor ulcerogenic action and lower acute toxicity.
摘要
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