Kerley S W, Pierce P, Thomas J
Department of Pathology, Mayo Clinic, Rochester, Minn.
Arch Pathol Lab Med. 1992 Feb;116(2):195-7.
Cystosarcoma phyllodes of the prostate is a rare neoplasm, occurring in adult men. It closely resembles the not uncommon tumor of the female breast and usually behaves in a similar manner. This case of benign cystosarcoma phyllodes of the prostate occurred in a 53-year-old man who presented with increasing abdominal girth and underwent exploratory laparotomy and removal of the 11.2-kg tumor. It was remarkable for its very large size and the presence of foci of well-differentiated adenocarcinoma, prostatic acinar type. The glandular epithelium of both the phyllodes tumor and the carcinoma were immunoreactive for cytokeratin, epithelial membrane antigen, prostate-specific antigen, and prostate-specific acid phosphatase. The presence of typical prostatic type adenocarcinoma and this immunoreactivity pattern strongly supports a prostatic origin for this rare neoplasm.
前列腺叶状囊肉瘤是一种罕见的肿瘤，发生于成年男性。它与女性乳房中较为常见的肿瘤极为相似，通常表现也类似。该例前列腺良性叶状囊肉瘤发生在一名53岁男性身上，患者因腹围增大就诊，接受了剖腹探查并切除了重达11.2千克的肿瘤。其显著特点是体积非常大，且存在高分化腺泡型前列腺腺癌灶。叶状肿瘤和癌的腺上皮细胞角蛋白、上皮膜抗原、前列腺特异性抗原和前列腺特异性酸性磷酸酶免疫反应均呈阳性。典型的前列腺型腺癌的存在以及这种免疫反应模式有力地支持了这种罕见肿瘤起源于前列腺。
